重組小鼠巨噬細(xì)胞集落刺激因子

M-CSF 也稱為 CSF-1，是一種四α螺旋束細(xì)胞因子，是巨噬細(xì)胞存活、增殖和分化的主要調(diào)節(jié)劑 。M-CSF 蛋白對于破骨細(xì)胞祖細(xì)胞的存活和增殖也至關(guān)重要。M-CSF 還可啟動(dòng)和增強(qiáng)巨噬細(xì)胞對腫瘤細(xì)胞和微生物的殺傷，調(diào)節(jié)巨噬細(xì)胞釋放細(xì)胞因子和其他炎癥調(diào)節(jié)劑，并刺激胞飲作用 。

(純度) Purity

≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining).

(內(nèi)毒素) Endotoxin

≤10 EU/mg by the LAL method.

(生物活性) Bioactivity

The activity is determined by the dose-dependent proliferation of murine NFS-60 cells is ＜ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 E7 units/mg.

(種屬) Species

Mouse

(表達(dá)系統(tǒng)) Expression System

CHO

(預(yù)測分子量大小) Mol. Weight

26 kDa (monomer)

(表達(dá)區(qū)間) Expression Region

Lys33-Glu262

(標(biāo)簽) Tag Info

Tag free

(劑型) Formulation

Lyophilized

(溶液) Buffer

Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4.

(規(guī)格) Size：1mg

(復(fù)溶) Reconstitution

It is recommended to redissolve in sterile deionized water.

(運(yùn)輸) Shipping

The product is shipped with blue ice.

(存儲) Storage & Stability

36 months at -20°C to -80°C in lyophilized state;

6 months at -20°C to -80°C under sterile conditions after reconstitution;

7-10 days at 2°C to 8°C under sterile conditions after reconstitution;

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.?

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